Nr. 1 - 1. Quartal 1995

Autotransplantation of Pancreatic Islets

U. J. Hesse, B. J. Hering, R. G. Bretzel, K. Federlin, A. Elewaut, B. de Hemptinne

Autotransplantation of about 363 000 pancreatic islets (i.e. +/- 7000/ kg body weight) were sufficient to establish a stable normoglycemic metabolic state in a patient with diabetes mellitus. Standardized methods for islet isolation, quality control and transplantation were applied. Despite a reduction in C-peptid levels up to 60% following glucagon stimulation normoglycemia could be sustained without the need of exogenous insulin.

Keywords:

Autotransplantation, pancreatic islets, diabetes mellitus

Kurztitel:

Hesse, U. J. et al. (1995) TxMed 1:62

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