Nr. 3 - 3. Quartal 1994

Combined Liver Islet Transplantation: Indication and Problems

W. Timmermann, R. Engemann, R. G. Bretzel, B. J. Hering, K. Federlin, A. Thiede

Combined liver islet transplantation is a procedure for replacement of the function of liver and endocrine pancreas. It is indicated for the treatment of malignant tumors following upper abdominal exenteration or in liver transplantation in type I diabetics. This procedure seems not to induce complications exceeding those after isolated liver or islet transplantation. Sixteen operations have been done so far, 6 in diabetics and 10 in patients with carcinoma. The longest period of functioning islets observed in a diabetic was 49 months. The longest survival of a patient treated for tumor by upper abdominal exenteration was more than 42 months with a still functioning islet transplantat.

Keywords:

Liver transplantation, islet of Langerhans transplantation

Kurztitel:

Timmermann, W. et al. (1994) TxMed 3:227

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