Clinical Experience with a New “Minimally
Invasive Circulatory Support System” (CardioVention CORx-System) for
Coronary Artery Bypass
J. Wippermann, J. M. Albes, M. Kaluza, H. Brandes, M. Hartrumpf,
Th. Wahlers
Objective: Cardiopulmonary bypass (CPB) is
known to cause part of the postoperative systemic inflammatory
reaction and hemodilution. In order to reduce these problems a novel
technique based on a single disposable, compact arterio-venous loop
with an integrated centrifugal blood pump and oxygenating, air removal
and gross filtration capabilities (CardioVention GmbH, Seevetal,
Germany) has been developed. The applicability of this system and
patients outcome was investigated in our clinic.
Methods: Five consecutive patients (59,6 + 8,3 y) with good
left ventricular function (ejection fraction > 50 %) underwent
coronary bypass surgery with the new CardioVention CORx system.
Specific evaluation of handling, priming volume, hematocrite- and
hemoglobine values were performed. Serial blood samples were taken
prior to the onset, after initiation, before weaning of the CPB and 6
hours postoperatively.
Results: The peri- and postoperative course of all patients was
completely uneventful.
Postoperatively stay on ICU was 16,6 + 1,7 hours. Priming volume in
all cases was 820 ml. On pump the minimun hematocrite level was 37,2 +
3,2 %. The mean hemoglobine level after surgery was 6,3 + 1,5 mmol/l
versus 9,1 + 0,7 mmol/l. No transfusion of blood or blood- products
were needed in any patient.
Conclusions: In our initial experience the CardioVention CORx
system is suitable to maintain total extracorporal circulation with a
50% reduction of the priming volume. The likewise reduced foreign
surface of 25 % compared to standard CPB may be accompanied by less
inflammatory response.
(CVE. 2005; 10 (1): 13-17)
Key words: Low prime volume circuit,
Cardiovention, hemodilution, foreign surface-reduction
Jens Wippermann, M.D.
Cardiothoracic and Vascular Sugery
University Hospital Jena
Bachstr. 18
D-07743 Jena
Germany
E- mail: Jens.Wippermann@med.uni-jena.de
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