CARDIOVASCULAR
ENGINEERING
Journal for Extracorporeal Circulation, Assist Devices,Transplantation and Artificial Organs

Volume 8, 2003, No 1-2


A Neural Network-Based Controller for an Artificial Heart
M. J. Conlon, D. L. Russell, T. Mussivand

Background: A control system for a ventricular assist device (VAD) must be reliable and flexible, able to react to changes in the human circulatory system. Compared to traditional control strategies, neural network controllers adapt more easily to systemic changes. A neural network-based controller was designed to regulate the operation of a simple VAD and its performance was evaluated using a numerical simulation.
Methods:
The human circulatory system was modelled using thirteen first order differential equations, and this numerical model was used to tune and evaluate a neural network controller. The controller has four inputs (current pump output, current systolic fraction, previous diastolic force, and previous systolic force) and two outputs (suggested changes to the systolic and diastolic forces for the next beat) and is trained to behave as a fixed-rate controller under normal physical conditions, in an attempt to maintain a constant peripheral blood flow rate. The change in peripheral flow resistance is estimated by the controller, and used to adjust the cardiac output. In this study, the controller was trained to react to a drop in peripheral resistance by increasing the cardiac output.
Results: The controller is able to achieve its design goals, maintaining a peripheral blood flow rate of 4.8 l/min under nominal conditions. If the controller detects a drop in peripheral resistance, which might indicate (for example) a heightened activity level, it reacts by increasing the cardiac output. Simulated peripheral flow rates using the neural network controller are superior to those achieved using either a fixed-rate or full-fill, full-eject control strategy, as the neural network controller responds more effectively to changes in the circulatory system parameters.

(CVE. 2003; 8 (1/2): 32-39)

Key words: ventricular assist device, neural network, control, computer simulation, cardiovascular system, dynamics


Prof. Donald L. Russell
Department of Mechanical and Aerospace Engineering
Carleton University
1125 Colonel By Drive
Ottawa K1S 5B6, Ontario
Canada
E-mail: drussell@mae.carleton.ca



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