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CARDIOVASCULAR
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Volume 5, 2000, No 4 |
Transcranial
Measurement of Regional Cerebral Hemoglobin Saturation by Near-Infrared
Spectroscopy Provide Non-Invasive Information on Cerebral Venous Blood
Saturation in Infants and Children
H. Abdul-Khaliq, K. Rützler, D. Troitzsch, P. Ewert, O.
Kretschmar, F. Berger, P. E. Lange
Objective:
The aim of this study was to investigate the relationship between the
non-invasive spectroscopic measurement of rSO2 and the oxymetric determination
of the blood saturation in the jugular bulb in infants and children undergoing
routine cardiac catheterization.
Design:
Simultaneous determination of Regional cerebral hemoglobin saturation (rSO2) and
Jugular bulb venous saturation (SjO2) in infants and children undergoing routine
cardiac catheterization.
Patients
and participants:
38 infants and children (age 5 days-18.3 years, median 5,6 years) were included
in this study.
Interventions:
The rSO2 was measured continuously using a two chanel cerebral oxymeter (INVOSâ
3100A). The sensor was placed in a standardized location on the right temporal
head side. After routine oxymetric blood sampling in the superior vena cava the
oxymetric catheter was manipulated into the right jugular bulb. After
control of the catheter position by imaging the neck area blood sampling for
immediate determination of SjO2 was performed. Simultaneous values of the
rSO2 were documented.
Measurements
and results: Over
a range of (33-87%) SjO2, a significant linear correlation was found between the
spectroscopic measurement of rSO2 and the oxymetric determination of venous
blood saturation in the jugular bulb (r=0.94, p=0.0006), superior vena cava
(r=0.85, p=0.001). No significant correlation was found between rSO2 and the
venous blood saturation in the inferior vena cava (r=0.51, p=0.29) and arterial
blood saturation in the descending aorta (r=0.46, p=0.31).
Conclusion:
Measurement of rSO2 by NIRS may provide continuous non-invasive information on
cerebral venous blood saturation and thereby possibly on cerebral oxygen supply
and consumption. These may be of clinical value particularly in infants and
children undergoing cardiac surgery by means of hypothermic cardiopulmonary
bypass.
(CVE. 2000; 5 (4): 257-260)
Key words: regional cerebral hemoglobin saturation (rSO2), jugular bulb venous saturation (SjO2), arterial blood saturation (SaO2), near infrared spectroscopy (NIRS)
Hashim Abdul-Khaliq, M.D.
Abteilung für Angeborene Herzfehler und Kinderkardiologie
Deutsches Herzzentrum Berlin
Augustenburgerplatz 1
D-13353 Berlin
Germany
E-mail: abdul-khaliq@dhzb.de
PABST SCIENCE PUBLISHERS
Lengerich, Berlin, Riga, Rom,
Wien, Zagreb