CARDIOVASCULAR ENGINEERING

CARDIOVASCULAR
ENGINEERING

Journal for Extracorporeal Circulation, Assist Devices,Transplantation and Artificial Organs

Volume 3, 1998, No 1



Patients with Chronic Obstructive Pulmonary Disease Undergoing Coronary Artery Bypass Grafting Surgery

A. Michalopoulos, E. Papadakis, K. Triantafillou, S. Geroulanos, G. Palatianos

Abstract:
Background: There are conflicting results with regard to the impact of COPD history on early postoperative course in patients undergoing open heart surgery. Methods: We studied 867 patients who underwent consecutively CABG surgery, during a three-year period (1994-1997) in order to find the prevalence and the prognostic importance of COPD history on the postoperative course in patients undergoing CABG surgery. COPD patients were treated preoperatively with bronchodilators when indicated, until bronchospasm was under control. Results: History of COPD was found in 101 patients (11.6 %). They were 93 males (92.1%) and 8 females, of mean (± S.D.) age 58.8 (± 6.1) years. Severe, moderate and mild COPD was found in 18 (17.8%), 34 (33.7%), and 49 (48.5%) patients, respectively. COPD group included 72 (71.3%), patients with chronic bronchitis, 25 with predominant pulmonary emphysema, and 4 patients with unremitting bronchial asthma. Bronchodilators were received by 62 COPD patients before surgery. Respiratory complications developed in 24 COPD patients (23.7 %) and 122 patients (15.9 %) in the control group (P=0.06). Prolonged mechanical ventilatory support (> 1 d.) was needed by 7 COPD patients (6.9 %) and 46 patients (6 %) in the control group (P=0.8). Nosocomial infection developed in 5 COPD (4.9 %) and in 32 patients (4.2 %) of the control group (P=0.9). Mean ICU and hospital stays were 2.0 ± 1.1 and 8.1 ± 1.2 days, respectively in COPD group, and 1.8 ± 0.9 (P=0.04), and 7.9 ± 1.4 in control group (P=0.1). Total hospitalization costs were similar in both groups (P=0.4). Mortality rate was found to be l% in COPD patients and 0.9 % in control group (P=0.7). Conclusions: There was no statistically significant difference in morbidity and mortality rates between COPD patients and controi group after CABG surgery (P <0.05). preoperative pulmonary evaluation and appropriate pulmonary medication seems to be very essential for successful management on these patients.

Keywords:
coronary artery bypass surgery, chronic obstructive pulmonary disease (COPD), morbidity, mortality, outcome

Address for Correspondence:

Argyris Michalopoulos
M.D.
Cardiothoracic ICU
Onassis Cardiac Surgery Center
356 Sygrou Ave
17674
Athens
Greece
E-mail: amichalopoulos@hol.gr

Reference:
(CVE. 1998; 3 (1): 26-31)


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