CARDIOVASCULAR ENGINEERING

CARDIOVASCULAR
ENGINEERING

Journal for Extracorporeal Circulation, Assist Devices,Transplantation and Artificial Organs

Volume 2, 1997, No 4



Valve Replacement in the Elderly with Bovine Pericardial Bioprostheses - 15 Years’ Results -

C. M. A. Brandão, P. M. A. Pomerantzeff, L. B. Puig, M. Grinberg, L. F. Cardoso, F. Tarasoutchi, A. Lerner, N. A. G. Stolf, G. Verginelli, A. D. Jatene

Abstract:
The purpose of the study is to analyse the long-term results with valve replacement in the elderly group with the bovine pericardial bioprostheses developed by the Heart Institute of São Paulo. Between January 1982 and December 1995, 463 FISICS - INCOR bovine pericardial bioprostheses were implanted in 432 patients older than 65 years. The average age was 70,3 +/- 4,3 years, and 58,1% were male. We performed 286 aortic valve replacements, 144 mitral replacements, 16 mitral-aortic replacements, and 1 tricuspid replacement. There have been associated procedures in 158 patients (36,6%), the most frequent was myocardial revascularization (19,2%). The hospital mortality was 53 patients (12,2%), 18,7% for the mitral group, 7,7% for the aortic, and 18,8%for the double valve replacement. The linearized rates for calcification, thromboembolism, rupture, leak and endocarditis were 0,4; 0; 0,8; 0,1 and 0,1% patient-year. The actuarial survival curve was 31,4 +/- 14,1% in 12 years. Freedom from endocarditis was 99,4 +/- 0,6%, thromboembolism 100%, rupture 91,8 +/- 3,8% , calcification 95,4 +/- 2,2% and leak 99,7 +/- 0,3% in 12 years. In the late post-operative period, 293 patients (87,7%) were in NYHA functional class I. We conclude that the results with the FISICS- INCOR bovine pericardial bioprostheses were satisfactory in the group of elderly patients.

Keywords:
Bioprostheses, valve surgery, elderly

Address for Correspondence:

Carlos M. A. Brandão
M.D.
Heart Institute – HCFMUSP
Department of Surgery
Av. Dr. Eneas de Carvalho Aguiar
44
São Paulo – CEP: 05403-000
Brasil.

Reference:
(CVE. 1997; 2 (4): 267-270)


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