CARDIOVASCULAR ENGINEERING

CARDIOVASCULAR
ENGINEERING

Journal for Extracorporeal Circulation, Assist Devices,Transplantation and Artificial Organs

Volume 2, 1997, No 2



Cerebral Responses to Cardiopulmonary Bypass and Circulatory Arrest in Neonates

P. M. Kirshbom, R. M. Ungerleider

Abstract:
The use of cardiopulmonary bypass with or without circulatory arrest for the repair of congenital cardiac diseases can result in significant post-operative neurologic dysfunction. To understand better the causes of some of these complications, one must first review the responses of the brain to cardiopulmonary bypass with regard to the cerebral vasculature and cerebral metabolism. This review will focus on what has been learned in experimental and clinical studies concerning cerebral responses to cardiopulmonary bypass, hypothermia, and circulatory arrest.

Keywords:
Brain, cardiopulmonary bypass, circulatory arrest, cerebral metabolism, cerebral blood flow

Address for Correspondence:

Ross M. Ungerleider
M.D.
Duke University Medical Center
P.O. Box 3178
Durham
N.C. 27710
USA.

Reference:
(CVE. 1997; 2 (2): 130-132)


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