CARDIOVASCULAR ENGINEERING Journal for Extracorporeal Circulation, Assist Devices,Transplantation and Artificial Organs
	Volume 2, 1997, No 2

Advantages and Disadvantages of Perfluorocarbon Emulsions Used During Cardiopulmonary Bypass

C. P. Murrah, R. D. Spruell, W. L. Holman

Abstract:
A new generation of perfluorochemical (PFC) emulsions are entering clinical evaluation for use as erythrocyte substitutes during cardiac operations. PFC emulsions used in conjunction with a high PO2 substantially increase the dissolved oxygen (O2) content of blood. This additional O2, which is readily available for diffusion into tissue, increases the capacity of the pump oxygenator to deliver O2 to the body during cardiopulmonary bypass (CPB). The ability of PFC emulsions to dissolve O2 in the plasma fraction of blood has important implications for the conduct of cardiac operations.

Keywords:
Perfluorochemical, blood, oxygen, myocardium, cardiopulmonary bypass

Address for Correspondence:

Reference:
(CVE. 1997; 2 (2): 113-119)

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