CARDIOVASCULAR ENGINEERING Journal for Extracorporeal Circulation, Assist Devices,Transplantation and Artificial Organs
	Volume 1, 1996, No 1

Heparinization in Children Undergoing Cardiopulmonary Bypass

P. G. Martin

Abstract:
The guiding principles of cardiopulmonary bypass heparinization were formulated in the 1970’s. However, since this time, earlier correction of congenital heart defects, the emergence of sensitive markers of coagulation, new monitoring technologies and improvements in the biocompatibility of circuit materials have each contributed to the feeling of uncertainty surrounding these standards. This review explores the main issues and the progress which has been made towards improving anticoagulation management for paediatric open-heart surgery.

Keywords:
heparin, heart surgery, coagulation, biocompatibility, cardiopulmonary bypass, protamine

Address for Correspondence:

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